UK Vascular and Endovascular Research Network

Groin wound Infection after Vascular Exposure (GIVE) Audit and Multicentre Cohort Study


Surgical site infection (SSI) is a major potential complication of any operation and is associated with morbidity and mortality. Typically, the cohort of patients encountered by vascular surgeons have multiple co-morbidities such as diabetes, obesity and cardiac disease which increase their risk of developing an SSI. The groin is the most common site for an incision in vascular surgery and is predisposed to infection due to local skin flora and its proximity to the anal canal and genitalia. Reported incidence of SSI following groin incision is as high as 27%. The morbidity and in severe cases, mortality, associated with groin infections in the setting of autogenous and synthetic grafts make it a priority for future research into strategies to effectively protect patients from this complication.


The Groin wound Infection after Vascular Exposure (GIVE) Audit is a prospective, multicentre, international audit aiming to capture contemporaneous data on infection rates of groin incision for arterial exposure in the UK and abroad. Three months of prospective data will be captured, follow up will be for up to 90 days. The primary outcome of interest will be to compare local practice(s) against widely recognised national criteria (NICE guidelines) for the prevention and management of SSI. The individual centres’ rate of groin infection will be calculated and compared to the cohort’s overall rate. Secondary analyses will explore risk factors for developing an SSI following a groin incision, and the accuracy of existing tools for predicting SSI. The results will be presented nationally and submitted for publication to a peer-reviewed journal. All participating individuals which fulfil the authorship criteria detailed in the protocol will be named as collaborative authors.

The GIVE Audit will build on the existing UK-wide network of collaborators since VERN was founded in 2014 and international links formed will support further collaboration with trainees globally – promoting the global surgery agenda of developing good research and clinical practice in high, middle and low-income countries.

Current Progress:

Currently 28 centres from 6 countries have registered with their local audit departments and are set up for data collection since launch in January 2019. Nineteen other centres from a further 2 countries have expressed interest and are awaiting registration. A benefit of this audit is its flexibility in starting dates and there is still time to register your centre for data collection. The deadline for registration is May 2019 for UK centres, international centres wishing to participate may have further time to allow for compliance with their respective national ethical regulations. To find out if your centre is registered or how you can contribute to the GIVE Audit contact